Can a page pass a variable to a design studio variable

I’ve returned to skuid post-retirement! And finding myself versioned up from v1 to v2.

In converting page CSS code to Design System variables, I’m wondering if each css combination will require its own style variant. I would like to have one style variant (called “Highlight”) that allows the page to indicate a background color and a text color. Does the Design System allow that?
Otherwise I presume I will need something like Highlight1, Highlight2, etc., or HighlightBW, HighlightRedText, etc.

Since the Community pages have changed since 2019, I would not object to suggestions I post such questions differently. Thanks!