Greg, is this Safari on Mac, or iOS? I’ve found this knowledge article from Salesforce that sounds very relevant.
https://help.salesforce.com/articleView?id=000269462&language=en_US&type=1
If this is affecting non-Skuid plugins as well, it sounds like it might be more related to interoperability between Salesforce and Safari.
Here is another link that seems related - it sounds like this has come up in the recent past for others. https://success.salesforce.com/answers?id=9063A000000e1jvQAA
Are you able to safely try any of the recommendations in either of these links?
