If you want to keep some of the standard salesforce pages that deliver good value (like profile) you can add custom links to your navigation and include the url parameter “&isdtp=vw” to the end. So this
url /_ui/core/userprofile/UserProfilePage?tab=sfdc.ProfilePlatformFeed&isdtp=vw
Will bring the user profile page without any sf header. Not perfect, but better.
